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Question February 3, 2012
Can a sperm lives with out nuclei? If so, why can't we use sperms as a carriers in drug delivery(tissue targeting)?Answer February 3, 2012
1 LIKES + LIKESperm cells actually have nuclei – so it’s not really right to say that they can live without nuclei. I’m not sure if sperm can be used in tissue targeting, but specific tissue targeting is something that is currently a developing innovative field in drug design. Anticancer agents are being targeted to cancer cells that express specific antigens using Antibody-Drug-Conjugates or ADCs. Novel diabetes treatments are being targeted to the liver or pancreas by engaging specific liver transporters and/or designing drugs with specific physical properties. There are even selective estrogen receptor modulators in development/on the market that specifically target bone estrogen receptors and not the breast or uterus receptors. New innovations in this area will certainly bring efficacious medicines with improved safety profiles. -
Mikael Dolsten’s Letter to the NYT Addresses our Commitment to R&D December 5, 2011
Mikael Dolsten, Pfizer's President of Worldwide Research and Development, recently submitted a <a href="http://www.nytimes.com/2011/12/05/opinion/pfizers-investments.html?_r=2&scp=1&sq=Mikael%20pfizer&st=cse">letter to the editor </a>of the <em>New York Times </em>in response to an article the publication ran on Pfizer's approach to R&D and shareholder investment. Mikael made the point that Pfizer is investing in areas of unmet medical need, as demonstrated by our recent ground breaking on the Centers for Therapeutic Innovation... -
How to Do Well at a Science Fair (or help a kid do so) April 22, 2011
One thing that science literate individuals are frequently asked for help with is to assist with science fair entries. Many people want to help their kids do well in these because they not only teach the very practical aspects of the scientific method but, when done well can help students get in to a good college and assist in obtaining financial aid for college. Having been a judge at a number of science fairs as well as having coached students through the process, I thought I would offer some advice on how to do well. 1) Find... -
Join Pfizer’s Medical Education Group for a ‘Social Media and CME’ Webinar September 2, 2010
<h3><strong>Please join us as we host a</strong> <em>First Friday Webinar Series</em>!</h3> On Friday, September 10<sup>th</sup>, 2010 the Medical Education Group (MEG) at Pfizer will host the next webinar in a series of monthly webinars aimed at maintaining an open and transparent dialog about independent medical education, grantsmanship, adult learning, and evaluation. <strong>CONFERENCE DETAILS:</strong> Meeting title: <em><strong>Pfizer Medical Education Group (MEG): First Friday Webinars</strong></em> Date:...
